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Antipruritic (Anti-Itch) Uses For the temporary relief of itching associated with minor skin irritations, inflammation, and rashes due to eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, jewelry, seborrheic dermatitis, psoriasis, and for external genital, feminine, and anal itching. Those that have developed jock itch will need to apply antifungal medications to clear away the spores. Making an effort to keep the skin, particularly around the groin, dry will help to prevent infections in the future. 7. Stasis Eczema. Stasis or gravitational eczema causes purple or reddish, itchy and swollen patches to appear on the lower legs. Diphenhydramine, an antihistamine, is used to relieve the itching of insect bites, sunburns, bee stings, poison ivy, poison oak, and minor skin irritation. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Diphenhydramine topical comes in ... Start studying Chapter 21. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Jun 30, 2016 · Anti-itch cream is a form of numbing medication that typically includes a small amount of hydrocortisone that can be applied to the skin topically. The over-the-counter cream can interfere with ... Drugs such as Tenoxicam, rectal diclofenac, pre-operative oral gabapentin, intravenous 5-HT3 antagonists, droperidol and subhypnotic dose of propofol have shown positive results for prevention of neuraxial opioid-induced pruritus and therefore, may be considered as possible prophylactic therapy.